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Reflux disease of the esophagus occasionally leads to release of inflammatory mediators, which may affect the atrial myocardium and other elements of the cardiac conduction pathways. Recently, a potential association between gastroesophageal reflux disease (gerd) and af development has been proposed due to the close anatomic vicinity of the oesophagus and the left atrium. Heartburn is a burning feeling in the chest caused by stomach acid travelling up towards the throat (acid reflux)

Refluxed acid through a compromised lower esophageal sphincter can produce burning chest pain that can be misinterpreted by patients and clinicians alike as cardiac chest pain, prompting potentially unnecessary cardiac workups. Heartburn is a misleading term—the acidic backwash from acid reflux or gastroesophageal reflux disease (gerd) actually affects the esophagus, which runs alongside the heart. Of the over eight million emergency room visits for chest pain each year, severe heartburn (known as gastroesophageal reflux disease, or gerd) accounts for over half the cases in which actual heart problems are ruled out.

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